BioCryst — Birmingham
BioCryst announced that it will close its Birmingham Discovery Center of Excellence by the end of 2026. The physical research site can be identified, but Sentinel did not resolve a defensible exact-site EPA environmental identity for it; that negative result is preserved rather than converted into a weak regulatory alert.
Facility identity
Operation: BioCryst Discovery Center of Excellence
Address: 2100 Riverchase Center, Building 200, Suite 200, Birmingham, AL 35244
Closure announced: June 29, 2026
Expected closure: by end of 2026
Exact-site EPA FRS/program ID: unresolved in the current evidence set.
What the evidence supports
BioCryst's SEC filing and company announcement establish the decision to discontinue internal discovery programs and close the Birmingham facility. Published scientific work by BioCryst researchers independently identifies the Discovery Center of Excellence at 2100 Riverchase Center, Building 200, Suite 200.
The environmental-registry layer is different: no exact-site EPA identity was strong enough in the current research to publish as the regulated Birmingham facility. For Sentinel, that is a meaningful boundary result rather than missing data to be papered over.
Evidence boundary
No nearby, historical, similarly named or weakly geocoded EPA record is inherited into this event. Until an exact-site regulatory identity is defensibly resolved, this remains a boundary-negative case rather than an asserted permit or compliance issue.
Sources
BioCryst — June 29, 2026 closure announcement
U.S. SEC — BioCryst Form 8-K
Beilstein Journal — published BioCryst research identifying the Birmingham site